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IL-13

   Also found in: Encyclopedia 0.01 sec.
IL-13,
abbreviation for interleukin-13.


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Another key mediator in asthma is IL-13, a cytokine that promotes B-cell differentiation, capable of inducing isotype switching leading to increased IgE production; IL-13 has also been shown to contribute to airway hyperresponsiveness (2, 24).
Th-2 cells, which modulate humoral immunity or antibody production, produce IL-4, IL-5, IL-6, IL-10, and IL-13.
Expulsion of Trichuris muris in experimental models requires the participation of interleukin (IL)-1a, IL-1ß,4 IL-4, IL-9, and IL-13 to polarize the T-helper response.
 
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