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IGF-I |
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IGF-I see somatomedin C. IGF-I Insulin-like growth factor I, somatomedin-C A polypeptide hormone structurally similar to proinsulin, synthesized in the liver and fibroblasts, giving fibroblasts a paracrine function; serum levels correlate with development of 2º
sex characteristics in puberty ↑ in Acromegaly, gigantism ↓ in starvation, anorexia nervosa, African pygmies, ↓ somatomedins, Laron dwarfism, kwashiorkor, liver disease in children, GH deficiency, hypopituitarism How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Insulin-like growth factor I, or IGF-I for short, is a hormone that appears to promote the growth of both normal and malignant cells in the breast. Giving diabetic rats daily injections of IGF-I for 8 weeks almost completely reversed this process, he and his colleagues report in the November AMERICAN JOURNAL OF PATHOLOGY. IPLEX is approved in the United States as the only once daily treatment for children with short stature associated with severe primary IGF-I deficiency (Primary IGFD). |
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