FABP6

(redirected from I-BAP)

FABP6

A gene on chromosome 5q23-q35 that encodes the ileal fatty acid-binding protein that stimulates gastric acid and pepsinogen secretion, and which binds bile salts and bilirubins. Isoform 2 is expressed in the lower GI tract and is essential for the survival of colon cancer cells in response to bile acid-induced apoptosis.
References in periodicals archive ?
2] reported an increase in serum I-BAP concentrations of 104% between pre- and postmenopausal women.
2 of our original paper [1] may on first glance suggest that I-BAP discriminates better between nonskeletal and skeletal diseases than does BAP enzyme activity (E-BAP), this is not supported by the data set.
As previously reported by Withold [4], only 17% of patients receiving renal transplants had serum TAP values within the reference interval but increased serum concentrations of I-BAP.