hypoaldosteronism


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hypoaldosteronism

 [hi″po-al-dos´ter-ōn-izm]
deficiency of aldosterone in the body.

hy·po·al·dos·ter·on·ism

(hī'pō-al-dos'tĕr-on-izm),
A condition due to deficient secretion of aldosterone; can occur in two forms: as part of generalized adrenocortical insufficiency; or as a selective deficiency caused by a primary defect of the adrenal gland or a defect in aldosterone biosynthesis.

hypoaldosteronism

A condition characterized by ↓ aldosterone secretion, often with ↓ renin release by kidney Clinical Most Pts are 50-70, have unexplained, chronic, asymptomatic hyperkalemia and moderate renal failure–creatinine ≥ 15 mL/min, muscle weakness, arrhythmias Associated conditions DM–50%, SLE, myeloma, renal amyloidosis, sickle cell anemia, cirrhosis, AIDS Management ↓ K+ consumption

hy·po·al·dos·ter·on·ism

(hī'pō-al-dos'tĕr-on-izm)
Condition due to deficient secretion of aldosterone.

hypoaldosteronism

deficiency of aldosterone in the body.
References in periodicals archive ?
CKD caused by diabetic nephropathy may be associated with hyporeninaemic hypoaldosteronism, which may cause hyperkalaemia despite relatively well-preserved kidney function.
These presenting symptoms are similar in infants with true hypoaldosteronism and CAH.
In the past, the diagnosis of primary hypoaldosteronism leaned heavily on the presence of hypokalemia.
These findings may be attributable to hyporeninemic hypoaldosteronism, subsequent to lead intoxication, as well as to inhibition of distal tubular Na-K-ATPase (100).
To the Editor: Hyporeninemic hypoaldosteronism was one of the postulated mechanisms mediating hyperkalemia in the case report by Dr.
Only type 4 renal tubular acidosis, NSAIDs, or hypoaldosteronism limit this homeostatic effect, he added.