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hyperpolarization |
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hyperpolarization /hy·per·po·lar·iza·tion/ (hi″per-po″ler-ĭ-za´shun) any increase in the amount of electrical charge separated by the cell membrane, and hence in the strength of the transmembrane potential.
hyperpolarization an increase in the amount of electrical charge on either side of a cell membrane so that there is an increase in the electric potential across the membrane.
hyperpolarization A change in the value of the resting membrane potential towards a more negative value. The inside of the cell becomes more negative than the outside. Hyperpolarization is inhibitory because the membrane potential moves away from the neuron's threshold at which an action potential could occur. Example: the retinal photoreceptor potentials when stimulated by light. See depolarization; receptor potential; resting membrane potential; synapse. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| This would increase the influx of chloride ions, leading to hyperpolarization of cells, preventing depolarization that would, in turn, decrease DA release. Baclofen binds with the GABAergic presynaptic receptor, causing hyperpolarization of the membrane and limiting the influx of calcium into the presynaptic terminal. |
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