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hyperpolarization

   Also found in: Wikipedia 0.03 sec.
hyperpolarization /hy·per·po·lar·iza·tion/ (hi?per-po?ler-i-za´shun) any increase in the amount of electrical charge separated by the cell membrane, and hence in the strength of the transmembrane potential.
hyperpolarization
an increase in the amount of electrical charge on either side of a cell membrane so that there is an increase in the electric potential across the membrane.


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This would increase the influx of chloride ions, leading to hyperpolarization of cells, preventing depolarization that would, in turn, decrease DA release.
Sustained exposure to the widely used herbicide atrazine: altered ... by Cory-Slechta, Deborah A. / Environmental Health Perspectives
Baclofen binds with the GABAergic presynaptic receptor, causing hyperpolarization of the membrane and limiting the influx of calcium into the presynaptic terminal.
Pharmacologic management of spasticity following stroke by Gallichio, Joann E. / Physical Therapy
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