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infantile cortical hyperostosis |
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hyperostosis /hy·per·os·to·sis/ (-os-to´sis) hypertrophy of bone.hyperostot´ic hyperostosis cortica´lis defor´mans juveni´lis an inherited disorder of limb fractures and bowing, thickening of skull bones, osteoporosis, and elevated levels of serum alkaline phosphatase and urinary hydroxyproline. hyperostosis cortica´lis generalisa´ta a hereditary disorder beginning during puberty, marked chiefly by osteosclerosis of the skull, mandible, clavicles, ribs, and diaphyses of long bones, associated with elevated blood alkaline phosphatase. hyperostosis cra´nii hyperostosis involving the cranial bones. hyperostosis fronta´lis inter´na thickening of the inner table of the frontal bone, which may be associated with hypertrichosis and obesity, most commonly affecting women near menopause. infantile cortical hyperostosis a disease of young infants, with soft tissue swelling over affected bones, fever, irritability, and periods of remission and exacerbation.
infantile cortical hyperostosis, a familial disorder characterized in an infant by subperiosteal bone formation over many bones, causing swellings and tenderness in the affected areas. The child also tends to be feverish and irritable. The mandible is most commonly involved. Radiographs indicate areas of new bone growth beneath the periosteum. It appears before 6 months of age and disappears during childhood. Also called Caffey's disease. hyperostosis (hī´p n 1. an excessive growth of bone, as in infantile cortical hyperostosis. n 2. a hypertrophy of bone. See also exostosis. hyperostosis, infantile cortical (Caffey's disease, Smyth's syndrome), n a disease of infants; of unknown cause and characterized by tender, soft tissue swelling that is followed by hyperostosis of the cortex of the underlying bone. The mandible, clavicle, and ulna are most frequently affected. infantile cortical hyperostosis Caffey disease An AD condition characterized by early onset hyperostosis and neo-osteogenesis, of facial and, less commonly, long bones, soft tissue swelling, hyperirritability, dysphagia, fever, pleuritis Lab
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