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hyperinfection syndrome

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Hyperinfection syndrome
A condition of massive infection in which threadworm larvae multiply rapidly and spread throughout the body. It is usually associated with damage to the immune system, the use of steroid medications, or malnutrition.
Mentioned in: Threadworm Infection

hyperinfection syndrome
Disseminated parasitosis in immunosuppressed, malignant, or malnourished hosts, caused by autoinfection with Strongyloides stercoralis Clinical Abrupt onset of high fever, abdominal pain, bloating, intestinal ulcerations, gram-negative sepsis and shock; intense transpulmonary nematodal migration results in dyspnea, cough, hemoptysis Treatment Thiabendazole Prevention Wear shoes, boil water


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2), (3) During autoreinfection, the larvae disseminates into the intestinal track, pulmonary tissue, and skin, resulting in a hyperinfection syndrome with a fatality rate of 90%.
In HIV-infected patients, the presence of peripheral eosinophilia should always raise the suspicion of the strongyloides hyperinfection syndrome.
Abstract: Strongyloides hyperinfection syndrome is one of several clinical manifestations of strongyloidiasis and has a mortality rate exceeding 85%.
 
 
 
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