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transplant rejection |
Also found in: Dictionary/thesaurus, Legal, Financial, Encyclopedia, Wikipedia, Hutchinson | 0.02 sec. |
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transplant 1. an organ or tissue taken from the body and grafted into another area of the same individual or another individual. 2. to transfer tissue from one part to another or from one individual to another. ovum transplant see ovum transplant. transplant rejection see rejection. transplant rejection Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by optimal
matching of MHC antigens and ABO blood groups and ameliorated with immunosuppressants–eg, cyclosporin, tacrolimus, rapamycin Exceptions of TR Corneal transplants, identical twins. See Graft-versus-host disease, HLA, MHC, Tissue typing. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Hyperacute rejection happens immediately after the organ is transplanted where the organ necroses and then fails; In past xenotransplants, surgeons could avoid hyperacute rejection by using organs from chimpanzees, the primate genetically most like humans. reported they have successfully cloned the world's first miniature swine with a specific gene that causes hyperacute rejection eliminated. |
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