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human herpesvirus 6

   Also found in: Acronyms, Wikipedia 0.01 sec.
human herpesvirus 6,
a T-cell lymphotrophic virus belonging to the subfamily Betaherpesvirinae that has a high affinity for CD4 lymphocytes. It exists as two variants, A and B. Variant A is isolated mainly in immunocompromised individuals. Variant B causes roseola infantum. Most healthy adults carry the virus and are asymptomatic; infection results in lifelong persistence. See also herpesvirus, roseola infantum.


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Much remains to be learned about the pathogenic role of [beta]-herpesviruses (cytomegalovirus [CMV], human herpesvirus 6 variants A and B [HHV-6A and HHV-6B], and human herpesvirus 7 [HHV-7]) in immune-compromised children.
1,2) The histopathologic and clinical characteristics of this disease suggest a viral etiology, such as those viruses capable of infecting lymphocytes, including Epstein-Barr virus, (3-6) cytomegalovirus, 4 parvovirus B19, (5) human herpesvirus 6 (HHV-6), (7-10) and human herpesvirus 8 (HHV-8).
After a May 4 inspection, FDA determined that Panbio was marketing the product, Human Herpesvirus 6 IgM and IgG IFA Kits, without a PMA.
 
 
 
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