Herpesviridae

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Her·pes·vir·i·dae

(her'pēs-vir'i-dē),
A heterogeneous family of morphologically similar viruses, all of which contain double-stranded DNA and infect humans and a wide variety of other vertebrates. Infections produce type A inclusion bodies; in many instances, infection may remain latent for many years, even in the presence of specific circulating antibodies. Virions are enveloped, ether sensitive, and vary up to 200 nm in diameter; the nucleocapsids are 100 nm in diameter and of icosahedral symmetry, with 162 capsomeres. The family is subdivided into three subfamilies Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae, and includes herpes simplex virus, varicella-zoster virus, cytomegalovirus, and Epstein-Barr virus (all of which infect humans), pseudorabies virus of swine, equine rhinopneumonitis virus, infectious bovine rhinotracheitis virus, canine herpesvirus, B virus of Old World monkeys, several viruses of New World monkeys, virus III of rabbits, infectious laryngotracheitis virus of fowl, Marek disease virus of chickens, Lucké tumor virus of frogs, and many others.

Her·pes·vir·i·dae

(hĕrpēz-viri-dē)
A heterogeneous family of morphologically similar viruses, all of which contain double-stranded DNA and infect humans and a wide variety of other vertebrates. Infections produce type A inclusion bodies; in many instances, infection may remain latent for many years, even in the presence of specific circulating antibodies.

Herpesviridae

(hər″pēzvi´rô ide),
n one of the major virus families, to which the herpes simplex, varicella zoster, and Epstein-Barr viruses belong. Viruses in this family have a double-stranded linear molecular structure with icosahedral symmetry.

Herpesviridae

a family of viruses, the members of which are about 150 nm in diameter, enveloped, with a nucleocapsid of about 100 nm in diameter, composed of 162 capsomers and contain a large, double-stranded DNA. The viruses replicate in the nucleus of the infected cell, where they induce the formation of a characteristic inclusion body; some also induce formation of a cytoplasmic inclusion body. The herpesviruses are classified into three subfamilies: (1) Alphaherpesvirinae, which are rapidly growing viruses that cause acute diseases, except Marek's disease which causes tumors in chickens; (2) Betaherpesvirinae, which are slow growing, highly cell-associated viruses, also called cytomegaloviruses, which produce subtle diseases with a prolonged clinical course; and (3) Gammaherpesvirinae, some of which produce low grade, prolonged clinical illness typified by infectious mononucleosus/glandular fever of humans, caused by Epstein-Barr virus, and probably a similar disease of horses caused by equine herpesvirus 2; the primate viruses are associated with tumors.
The important diseases of animals caused by herpesviruses are dealt with under their individual headings: aujeszky's disease, infectious bovine rhinotracheitis, infectious pustular vulvovaginitis, equine viral abortion, equine viral rhinopneumonitis, equine coital exanthema, equine herpesvirus 2 infection, the Allerton form of lumpy-skin disease, the generalized infection of cattle with bovine herpesvirus 2, bovine herpes mammillitis, the African 'wildebeest-associated' malignant catarrhal fever, canine herpesvirus respiratory, genital and neonatal infections, feline viral rhinotracheitis. In birds there are infectious laryngotracheitis, pigeon herpesvirus, duck plague and marek's disease.
References in periodicals archive ?
Hydrocortisone activation of human herpes virus 8 viral DNA replication and gene expression in vitro.
The present Competitive Intelligence Report about Herpes Virus Vaccines & Therapeutics provides a competitor evaluation in the field of prophylactic vaccines and therapeutic antibodies and small molecules against infection caused by herpes simplex virus (HSV) type 1 and/or type 2 and varicella zoster virus (VZV) or human herpes virus type 3 (HHV-3) as of December 2012.
He added that the same kind of motor was also likely present in other viruses, such as the human herpes virus.
burgdorferi, hepatitis A, B, and C, human herpes virus 6, herpes simplex virus 1 and 2, Epstein-Barr virus, cytomegalovirus, and tickborne encephalitis virus.
A group of researchers there reported finding a link between MS and the human herpes virus known as HHV-6.
Others are human papillomavirus (HPV), a cause of cervical cancer; HTLV-I, which can cause a rare cancer or a paralytic illness; mycoplasma, which causes urethritis; mobiluncus, which causes vaginosis; and human herpes virus 8, which causes Kaposi's sarcoma and lymphoma.
This volume of the proceedings of the Academy's meeting "Cell Signaling World: Signal Transduction Pathways as Therapeutic Targets" held January 2006 in Luxembourg addresses current research on signal transduction in such topics as bacterial endotoxin, expression and suppression of cytokine signaling-3, control of human herpes virus Type 8, regulation of apolipoprotein B secretions but not lipids by tumor necrosis factors, signaling pathways used by HSV-1 and by proteinase activated receptors and melphalan's role in the reduction of the severity of experimental colitis.
One study caused a stir by suggesting that human herpesvirus 6 might be a frequent cause of febrile convulsions in young children, but results of a subsequent study contradicted that: It found that the rate of human herpes virus 6 among children was no different between those who had febrile seizures and those who didn't
pylori, HTVL-1 and the human herpes virus associated with the genesis of cancer.
The risk of disease from an oncogenic virus, including human papilloma virus, Epstein-Barr virus, and human herpes virus 8, increases more than 10-fold if the CD4 count falls to 200 cells/[mu]L rather than 350 cells/{mu]L before treatment starts.
will present "Blockade of Expression of a Growth Factor Homologue Viral Interleukin 6 of Human Herpes Virus 8.