human endogenous retroviruses

human endogenous retroviruses (HERV)

Retrovirus-like sequences found in the human genome, thought to constitute the remains of true retroviruses that were absorbed through evolution. At least one is thought to be linked to expression of tumor cells. They are also thought to be involved in autoimmune disorders such as multiple sclerosis.
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References in periodicals archive ?
cgi) to search for similar sequences in the nucleotide collection database, which includes exogenous viruses and human endogenous retroviruses such as HERV-K.
Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity.
Possible role of DNA hypomethyfation in the induction of SLE; relationship to the transcription of human endogenous retroviruses.
HERVd: The human endogenous retroviruses database: update.
Patients with autoimmune diseases often have elevated antibody levels to certain structural proteins of human endogenous retroviruses (HERVs), suggesting a possible role for these viruses in autoimmune disease.
Unlike viruses for the common cold or those associated with AIDS, human endogenous retroviruses no longer bother with the tedious effort involved in infecting and taking over cells.
In an independent search for new human endogenous retroviruses, Francois Mallet and his colleagues at the Ecole Normale Superieure in Lyon, France, also identified the gene for syncytin.

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