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Howell-Jolly bodies

   Also found in: Encyclopedia 0.01 sec.
Howell-Jolly bodies
[hou′əl jol′ē]
Etymology: William H. Howell, American physiologist, 1860-1945; Justin M.J. Jolly, French histologist, 1870-1953
spheric and granular inclusions in the erythrocytes observed on microscopic examination of stained blood smears. They are most commonly seen in people who have hemolytic or pernicious anemia, leukemia, thalassemia, or congenital absence of the spleen and in those who have had a splenectomy.

Howell-Jolly bodies
small, round or oval bodies, probably nuclear remnants, seen in erythrocytes when stains are added to fresh blood and found in various anemias and after splenectomy or reduced splenic function.


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The abnormally high number of Howell-Jolly bodies in our patient was indicative of altered splenic function.
The sister's CBC showed the presence of rare spherocytes and Howell-Jolly bodies.
 
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