Without sufficient hormone-sensitive lipase activity, obese people may have more trouble getting access to the energy stored in their fat cells, possibly making it more difficult to lose weight.
A blend from Mediterranean citrus fruit and a South American seed has been shown to increase hormone-sensitive lipase activity in white adipose tissue cells, restoring their ability to free up--and burn off--their stores of excess energy.
Targeted disruption of hormone-sensitive lipase
results in male sterility and adipocyte hypertrophy, but not in obesity.
Adipose triglyceride lipase and hormone-sensitive lipase
protein expression is decreased in the obese insulin-resistant state.
Long-term regulation of lipolysis and hormone-sensitive lipase by insulin and glucose.
Hormone-sensitive lipase from adipose tissue of rat.
Effect of dietary saturated fatty acids on intracellular free fatty acids and kinetic properties of hormone-sensitive lipase
of rat adipocytes.
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase
These compounds appear to stimulate an enzyme called protein kinase A, which in turn activates hormone-sensitive lipase
to break down fat, releasing fatty acids and glycerol.
Based on the gene expression profile, up-regulation of hormone-sensitive lipase
and enhancement of the lipolytic activity by the treatment of adipocytes with cyanidin 3-glucoside, have been demonstrated.
Relationships between lipolysis induced by various lipolytic agents and hormone-sensitive lipase
in rat fat cells.
Lipoprotein and hormone-sensitive lipases
in porcine adipose tissue.