dimer

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Related to Homodimers: dimeric, Heterodimerization, Homodimeric

dimer

 
1. a compound formed by combination of two identical simpler molecules.
2. a capsomer having two structural subunits.
D-dimer a fragment of fibrin that is formed as a result of fibrin degradation. A positive test for its presence in the blood is suggestive of conditions such as thrombotic disease, sickle cell crisis, malignancy, disseminated intravascular coagulation, or recent surgery.

di·mer

(dī'mĕr),
A compound or unit produced by the combination of two like molecules; in the strictest sense, this occurs without the loss of atoms (thus, nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (for example, a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

dimer

/di·mer/ (di´mer)
1. a compound formed by combination of two identical molecules.
2. a capsomer having two structural subunits.

dimer

[dī′mər]
Etymology: Gk, di, twice, meros, parts
a compound formed by the union of two radicals or two molecules of a single simpler compound.

di·mer

(dī'mĕr)
A compound or unit produced by the combination of two like molecules; in the strictest sense, without loss of atoms (thus nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (e.g., a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

dimer

a molecule made by the joining of two molecules of the same kind, i.e. two MONOMERS. Ultraviolet light can induce THYMINE DIMERS in DNA.

dimer

chemical compound formed by the union of two identical molecules.
References in periodicals archive ?
Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
San Francisco, CA) announced that scientific collaborators have presented additional clinical results on HERmark, the company's novel oncology assay, as a means to measure HER2 total protein and homodimer levels and predict response to Herceptin (trastuzumab) in patients with metastatic breast cancer at the 44th ASCO Annual Meeting taking place in Chicago, Illinois.
For example, p50/p50 homodimers can translocate to the nucleus but do not induce transcription of inflammatory genes.
The nine subunits of ADH can combine to form homodimers (i.
The fuzzy oil drop model to identify the complexation area in protein homodimers
PERK can form homodimers and is activated by trans-autophosphorylation which phosphorylates the [alpha]-subunit of eukaryotic translation initiation factor-2[alpha] (eIF2[alpha]) leading to inhibition that prevents additional accumulation of newly synthesized proteins into the ER (Zhang and Kaufman, 2008).
The VDR forms homodimers or heterodimers with the retinoid X receptor (RXR, NR2B), to allow specific DNA binding.
All NOS proteins are homodimers that transfer electrons from NADPH to the haem in the oxygenase domain where there are also binding sites for [BH.
2+] concentration, which occurs for example after axon injury, dissociates DLK-1S from DLK-1L and allows the formation of DLK-1L homodimers, which are the active form.
From there, their glycosylated residues project towards the extracellular space, overlapping and forming homodimers in a calcium-dependent manner.