rosette (redirected from Homer Wright rosette)

rosette /ro·sette/ (ro-zet´) [Fr.] any structure or formation resembling a rose, such as (a) the clusters of polymorphonuclear leukocytes around a globule of lipid nuclear material, as observed in the test for disseminated lupus erythematosus, or (b) a figure formed by the chromosomes in an early stage of mitosis.

---

Flexner-Wintersteiner rosette  a spoke- and wheel-shaped cell formation seen in retinoblastoma and certain other ophthalmic tumors.

Homer Wright rosette  a circular or spherical grouping of dark tumor cells around a pale, eosinophilic, central area that contains neurofibrils but lacks a lumen; seen in some medulloblastomas, neuroblastomas, and retinoblastomas or other ophthalmic tumors.

---

ro·sette (r-zt)

n.

1. The segmented or mature phase of Plasmodium malariae.

2. A grouping of cells characteristic of neoplasms of neuroblastic or neuroectodermal origin, in which a number of nuclei form a ring from which neurofibrils extend to interlace in the center.

---

rosette

any structure or formation resembling a rose, such as (1) the clusters of polymorphonuclear leukocytes around a globule of lipid nuclear material, as observed in the test for disseminated lupus erythematosus, or (2) a figure formed by the chromosomes in an early stage of mitosis.

---

rosette of Furstenberg

the white ridges of mucous membrane that radiate from the internal orifice of the teat of ruminants.

rosette inhibition test

used to detect the presence of 'early pregnancy factor' but has problems of application and limited usefulness.