Hodgkin disease


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

Hodg·kin dis·ease

(hoj'kin),
a disease marked by chronic enlargement of the lymph nodes, often local at the onset and later generalized, together with enlargement of the spleen and often of the liver, no pronounced leukocytosis, and commonly anemia and continuous or remittent (Pel-Ebstein) fever; considered to be a malignant neoplasm of lymphoid cells of uncertain origin (Reed-Sternberg cells), associated with inflammatory infiltration of lymphocytes and eosinophilic leukocytes and fibrosis; can be classified into lymphocytic predominant, nodular sclerosing, mixed cellularity, and lymphocytic depletion types; a similar disease occurs in domestic cats.
Synonym(s): Hodgkin lymphoma, lymphadenoma (2)

Hodg·kin dis·ease

(hoj'kin di-zēz')
A disease marked by chronic enlargement of the lymph nodes, often local at the onset and later generalized, together with enlargement of the spleen and often of the liver, no pronounced leukocytosis, and commonly anemia and continuous or remittent (Pel-Ebstein) fever; considered to be a malignant neoplasm of lymphoid cells of uncertain origin (Reed-Sternberg cells), associated with inflammatory infiltration of lymphocytes and eosinophilic leukocytes and fibrosis; can be classified into lymphocytic predominant, nodular sclerosing, mixed cellularity, and lymphocytic depletion type; a similar disease occurs in domestic cats.

Hodgkin,

Thomas, English physician, 1798-1866.
Hodgkin disease - malignant neoplasm of lymphoid cells of uncertain origin, associated with inflammatory infiltration of lymphocytes and eosinophilic leukocytes and fibrosis. Synonym(s): lymphadenoma
Hodgkin-Key murmur - a musical diastolic murmur.
Hodgkin sarcoma
non-Hodgkin lymphoma - a lymphoma other than Hodgkin disease.

Hodg·kin dis·ease

(hoj'kin di-zēz')
Disease marked by chronic enlargement of the lymph nodes, often local at the onset and later generalized, together with enlargement of the spleen and often of the liver.
References in periodicals archive ?
Lymph node histology revealed a pleomorphic infiltrate with Reed-Sternberg-like cells suspicious for Hodgkin disease.
It is striking that the histology depicted in the photomicrograph from this case very closely resembles lymphocyte-predominance Hodgkin disease and that the authors stated that the histology was "morphologically most similar to a Hodgkin's sarcoma but without any definite Reed-Sternberg cells.
Our patient was diagnosed with Hodgkin disease involving the mesenteric lymph nodes recovered from a right hemicolectomy for colonic adenocarcinoma.
Hodgkin disease infrequently presents below the diaphragm, and its occurrence in elderly males is more common in these sites.
He had no evidence of disease at last follow-up, 8 months after the diagnosis of Hodgkin disease.
Primary gastrointestinal Hodgkin disease in association with Crohn disease is a rare entity.
A mediastinoscopy with lymph node biopsy was performed and showed Hodgkin disease, nodular sclerosis type.
The association of Hodgkin disease and tuberculosis is not uncommon.
Traditionally, Hodgkin disease has been divided into 4 subtypes based on differences in the appearance of the neoplastic cells, as well as the components of the background.