max]) and Hill coefficient (h) were determined by non-linear regressions of the dose--response curves (for each drug and mixtures), fixing zero as the minimal effect ([E.
B] are the Hill coefficients for drug A and B, respectively.
5) by replacing n by h, called the Hill coefficient.
While the noise-free Hill coefficient (h) provides a good estimate of the number of binding sites only when there is strong positive cooperativity [5,8] ([beta]<<1 in Eq.
Bi-substrate kinetic model with an empirical Hill coefficient
B] characterize the interaction of ADP and PEP with the enzyme, and n is the Hill coefficient for PEP.
67-fold decreases in the Hill coefficient, respectively, compared with Hb incubated without GSH.
b) Hill coefficient (maximum slope of the Hill plot).
d] is the apparent dissociation constant and n is the Hill coefficient.
7 [mu]M with a remarkably high Hill coefficient of 3.
The cooperativity of respiratory pigments is characterized by the Hill coefficient
The variable H is the Hill coefficient
and is a measure of the degree to which the relationship between the number of molecules bound and the log of the free ligand concentration deviates from simple binding.