USP7

(redirected from Herpes virus-associated ubiquitin-specific protease)

USP7

A gene on chromosome 16p13.3 that encodes an enzyme which deubiquitinates target proteins (e.g., FOXO4, p53/TP53, MDM2, PTEN and DAXX). USP27 forms a complex with DAXX, MDM2 and RASSF1. It is widely expressed in various tissues and overexpressed in prostate cancer.
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