genetic disorder

(redirected from Heritable disease)
Also found in: Dictionary, Thesaurus.

genetic disorder

n.
A pathological condition caused by an absent or defective gene or by a chromosomal aberration. Also called hereditary disease.

genetic disorder

ge·net·ic dis·or·der

(jĕ-net'ik dis-ōr'dĕr)
A widely used but nonetheless imprecise term that denotes a condition or illness related to biologic inheritance.

Patient discussion about genetic disorder

Q. what makes Arthritis a genetic disease?

A. First of all, the term arthritis is a bit inaccurate: Arthritis denotes an inflammation of joints. There are many kinds of arthritis that may result from different causes, and therefore, are different diseases: septic arthritis (inflammation due to infection of joint) has much less genetic background than ankylosing spondylitis (an arthritis of the lower back joints that occurs almost exclusively in people with certain genetic background).

The arthritis with the genetic background are usually the autoimmune ones: Due to genetic determinants, the immune system of some people is programmed to recognize the various parts of the joints (and other organs as well) as foreign (i.e. like bacteria) and thus launches an attack on them. In normal immune system, that doesn't happen.

You may read more here:
http://en.wikipedia.org/wiki/Autoimmune_disease

Q. Is bipolar disease a hereditary problem? My only son is in his teens that is the age to enjoy life, but he cannot enjoy his life with his friends because we found that he is suffering from a bipolar condition. I feel so sad for him and though my care-free days have gone, I often think about how much fun I had at his age. I too suffered from a bipolar disorder and my mom too. Is bipolar disease a hereditary problem? I want him to help to enjoy his life.

A. I agree with you. No one should suffer because of hereditary problems. This is the same situation here as genes are passed from generation to generation. This information is inconclusive because many who may have had bipolar disorders did not have it checked out. Who is to say, how many people 50 years ago had it but dismissed it as being moody, or ill tempered. Doctors were not aware about this problem years ago. Some time back, someone who showed signs of a mental disorder was straight away shoved into a mental hospital and left to suffer. Besides they are often treated with electric shock therapy eventually getting out of control. Testing is still in progress to find out if genetics play a role but these theories may take several more years before they can have a better understanding.
http://www.youtube.com/watch?v=f7uKg7ujoig&eurl=http://www.imedix.com/health_community/vf7uKg7ujoig_film_mental_illness_released_strive_happiness?q=bipolar%20disease%&feature=player_embedded

Q. Is FMS heredetery? My mother was diagnosed with FMS and I would like to know what are the chances I’ll have it too.

A. Hereditary is not the right term. It’s not a genetic disease but The cause of fibromyalgia remains elusive. However, recent studies show that genetic factors can predispose individuals to a genetic susceptibility to fibromyalgia.

More discussions about genetic disorder
References in periodicals archive ?
Third, there is no agreement on which, if any, human heritable diseases should be corrected.
Select the species of your choice, and conduct an Internet search to determine what heritable diseases are of concern in that species.
In this report, we present the natural history of the Acadian Usher syndrome population and review the efforts our laboratories have undertaken to discover the mutation that causes this heritable disease.
We believe that it will continue to be a highly useful research tool for discovery of mutations linked to heritable disease and cancer.
Knowledge of the genetic makeup of our species, the genetic basis of heritable diseases, and the invention of technology to manipulate and fix mutant genes provides methods to treat the disease (1) .
Professor Chen has also identified the genetic basis of and developed DNA-based diagnosis for several major heritable diseases, and more recently, his team in Taiwan has uncovered genes/SNPs associated with drug-induced Stevens-Johnson syndrome and warfarin sensitivity.
He was the founding chair of the congressionally mandated Advisory Committee on Heritable Diseases in Newborns and Children, established to advise the Secretary of Health and Human Services about genetic testing in children, with particular emphasis on newborn screening.
As DNA sequencing has become an integral part of the clinical armamentarium for the diagnosis of certain heritable diseases, molecular pathologists and geneticists are increasingly faced with the challenge of providing medical interpretation for novel or rare mutations.
The Human Genome Project, the Human Genome Diversity Project, and the practice of genetic counseling for heritable diseases all have highlighted numerous medicolegal concerns.
markers for heritable diseases like Tay-Sachs among so-called Ashkenasi Jews).
Good laboratory practices for molecular genetic testing for heritable diseases and conditions.
Knowledge of basic brain embryology provides the foundation for making diagnoses of brain malformations, heritable diseases, congenital neoplasms and even disorders of postnatal development.