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hepatopulmonary syndrome

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hepatopulmonary syndrome,
arterial hypoxemia caused by pulmonary vasodilation in conjunction with chronic liver disease, usually occurring as a result of portal hypertension in cirrhosis.

hepatopulmonary syndrome
A condition in which hypoxemia due to intrapulmonary shunting and/or a V/Q mismatch develops in a Pt with liver cirrhosis; usually there is no apparent parenchymal lung disease, but Pts may have orthodeoxia, an unusual finding of ↑ hypoxemia with a change from the supine to the erect position; the pathogenesis of HPS is uncertain but may be due to an ↑ production of endogenous nitric oxide; shunting of HPS may respond to IV methylene blue


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Named after the Star Wars hero Luke Skywalker, Luke was diagnosed with hepatopulmonary syndrome, a rare complication of liver disease that causes an abnormal function of the lungs.
The ILTS will fund Michael Ramsay, MD, of Baylor University Medical Center, in Dallas, TX who will speak on Hepatopulmonary Syndrome and Portopulmonary Hypertension and Critical Aspects of Anesthesia for Liver Transplantation.
Papers cover pathophysiology, natural history, methods of evaluation, new drugs and therapeutic strategies, clinical issues, and emerging topics such as the role of coagulation disturbances, portopulmonary hypertension and the hepatopulmonary syndrome, hepato-renal syndrome, spontaneous bacterial peritonitis, and non-cirrhotic portal hypertension.
 
 
 
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