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ito cell
(redirected from Hepatic stellate cell)

   Also found in: Wikipedia 0.02 sec.
ito cell


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The activation of hepatic stellate cells is the common pathway to liver fibrogenesis, and in vitro studies have shown that acetaldehyde, a highly reactive toxic product of alcohol metabolism, can directly induce collagen gene transcription and promote liver fibrosis, even in the absence of necro-inflammatory changes (Moshage et al.
Friedman was the first to isolate and characterize the hepatic stellate cell, which is the key cell type responsible for scar production in liver.
 
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