heparan sulfate

(redirected from Heparin sulfate)
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Related to Heparin sulfate: keratan sulfate, dermatan sulfate

heparan sulfate

 [hep´ah-ran]
a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta, and lung; it is an accumulation product in several mucopolysaccharidoses.

hep·a·ran sul·fate

(hep'ă-ran sŭl'fāt),
A heteropolysaccharide that has the same repeating disaccharide as heparin but with fewer sulfates and more acetyl groups; accumulates in people with certain types of mucopolysaccharidosis.
Synonym(s): heparitin sulfate

heparan sulfate

/hep·a·ran sul·fate/ (hep´ah-ran) a glycosaminoglycan occurring in the cell membrane of most cells, consisting of a repeating disaccharide unit of glucosamine and uronic acid residues, which may be acetylated and sulfated; it accumulates in several mucopolysaccharidoses.

heparan sulfate

(hĕp′ə-răn)
n.
A glycosaminoglycan found on cell surfaces and basement membranes in mammals that regulates a wide variety of biological processes, including angiogenesis and blood coagulation. Also called heparitin sulfate.

heparan sulfate

a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta and lung; it is an accumulation product in several mucopolysaccharidoses.
References in periodicals archive ?
They have a core protein that is attached to the cell surface and they have these heparin sulfate chains that branch off.
No increase in proliferation was found after exposure to FGF-10, FGF-1 and heparin sulfate.
Children with Sanfilippo are missing an essential enzyme that breaks down a complex body sugar called heparin sulfate.
Often, its effect is enhanced by steroids, heparin sulfate, sodium bicarbonate, and antibiotics--the so-called DMSO cocktail.
The process used may include adsorption on calcium phosphate/hydroxyapatite, a hydrophobic matrix, a chelate matrix, a matrix on which heparin or a substance related to heparin, such as heparin sulfate or dextran sulfate, is immobilized, or a matrix that is coated with an immobilized monoclonal or polyclonal antibody directed against the protein to be isolated, or F(ab) or F(ab).

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