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heparin-induced thrombocytopenia
(redirected from Heparin induced thrombocytopenia)

   Also found in: Wikipedia 0.02 sec.
heparin-induced thrombocytopenia
Acquired thrombocytopenia affecting some heparin-treated Pts–HTPs, defined as a ↓ platelet count during or shortly after heparin exposure; HIT is a markedly prothrombotic disorder seen in Pts who are at a high baseline risk for venous thrombosis DiffDx Antiphospholipid antibody syndrome, DIC, Trousseau syndrome–migratory thrombophlebitis & malignancy, TTP/HUS, thrombocytopenia and 'showers' of microthrombi Clinical HIT occurs 6-10 days after heparin exposure Diagnosis Aggregation studies using platelets from Pts known to be sensitive to antibody; quantification of serotonin release from platelets radiolabeled with serotonin in assay using Pt serum


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The approval covers the use of the test for managing patients suffering from Heparin Induced Thrombocytopenia (HIT) who receive Refludan while undergoing cardiopulmonary bypass.
 
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