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heparan sulfate
(redirected from Heparan sulphate)

   Also found in: Wikipedia 0.09 sec.
heparan sulfate /hep·a·ran sul·fate/ (hep´ah-ran) a glycosaminoglycan occurring in the cell membrane of most cells, consisting of a repeating disaccharide unit of glucosamine and uronic acid residues, which may be acetylated and sulfated; it accumulates in several mucopolysaccharidoses.
heparan sulfate
a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta and lung; it is an accumulation product in several mucopolysaccharidoses.


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The heparan sulphate PG, syndecan, is attached to the cell membrane and plays a role in cell growth through binding growth factors, such as basic fibroblast growth factor, and acting as a co-receptor.
 
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