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heparan sulfate |
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heparan sulfate /hep·a·ran sul·fate/ (hep´ah-ran) a glycosaminoglycan occurring in the cell membrane of most cells, consisting of a repeating disaccharide unit of glucosamine and uronic acid residues, which may be acetylated and sulfated; it accumulates in several mucopolysaccharidoses. heparan sulfate a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta and lung; it is an accumulation product in several mucopolysaccharidoses. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In the body, heparan sulfate binds growth factors until the cells are ready to use them, says Kiick. Importantly, the authors found increased amounts of serum proteins, increased differential protein excretion, and increased amounts of heparan sulfate in the urine of DHF patients. Armand began his career at the University of Chicago in the early 1960's where he was involved in the isolation and structural characterization of heparan sulfate and dermatan sulfate from skin fibroblasts and from urine derived from patients with "Hurler Syndrome ", a form of mucopolysaccharidoses. |
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