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heparan sulfate |
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heparan sulfate /hep·a·ran sul·fate/ (hep´ah-ran) a glycosaminoglycan occurring in the cell membrane of most cells, consisting of a repeating disaccharide unit of glucosamine and uronic acid residues, which may be acetylated and sulfated; it accumulates in several mucopolysaccharidoses. heparan sulfate a sulfated mucopolysaccharide structurally related to heparin, which occurs normally in the liver, aorta and lung; it is an accumulation product in several mucopolysaccharidoses. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The GBM is a trilaminar membrane consisting of fibronectin, laminin, type IV collagen, and negatively charged heparan sulfate proteoglycans. Mutations in the E2 glycoprotein of Venezuelan equine encephalitis virus confer heparan sulfate interaction, low morbidity, and rapid clearance from blood of mice. In the body, heparan sulfate binds growth factors until the cells are ready to use them, says Kiick. |
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