He·noch-Schönlein purpura (h  nôk-, -nô -)n. A form of nonthrombocytopenic purpura occurring most commonly in boys and associated with pain or swelling of the joints, colic, vomiting of blood, passage of bloody stools, and sometimes inflammation of the kidneys. Also called allergic purpura, anaphylactoid purpura, Schönlein's disease, Schönlein-Henoch purpura. |
Henoch-Schönlein purpura
Anaphylactoid purpura, vascular purpura Internal medicine An acquired form of small vessel vasculitis with IgA-dominant immune deposits affecting small vessels–arteries, capillaries, venules, typically of
the skin, gut, and glomeruli, associated with arthralgia and/or arthritis; HSP is most common in younger Pts Clinical Red maculopapules on legs and buttocks, glomerulonephritis, abdominal pain ± infarction, diarrhea, fever, arthritis Lab IgA
deposits in basement membrane of skin and glomerulus Treatment NSAIDs, aspirin, steroids–eg, prednisone, especially in Pts with major abdominal pain or kidney disease Prognosis Usually self limited. See Small vessel vasculitis, Systemic
vasculitis.
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