equation /equa·tion/ (e-kwa´zhun) an expression of equality between two parts.
Henderson-Hasselbalch equation
Henderson-Hasselbalch equation a formula for calculating the pH of a buffer solution such as blood plasma.
Hen·der·son-Has·sel·balch equation (h n d r-sn-h sl-blk , -häsl-bäl )n. An equation expressing the pH of a buffer solution as a function of the concentration of the weak acid or base and the salt components of the buffer. |
Henderson-Hasselbalch equation
Etymology: Lawrence J. Henderson, American chemist, 1878-1942; Karl A. Hasselbalch, Danish biochemist, 1874-1962
the relationship among pH, the pKa of a buffer system, and the ratio of the concentrations of the weak acid and its conjugate base.
Henderson-Hasselbalch equation
an equation by which the pH of a buffer solution, blood plasma being such a one, can be determined:$$\hbox{pH=pK\'^\prime}+\log{[\hbox{BA}]\over[\hbox{HA}]}$$
where pK′ is the negative log of the dissociation constant of a weak acid in a buffer solution, [HA] is the concentration in the buffer solution of the weak acid and [BA] is the concentration of a salt of that acid.
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