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Helicobacter pylori |
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Helicobacter pylori A gramnegative rod-shaped bacterium that lives in the tissues of the stomach and causes inflammation of the stomach lining. Mentioned in: Indigestion, Ulcers Helicobacter pylori (he·li·kō·bakˑ·ter pī·lōˑ·rē), Helicobacter pylori Campylobacter pylori GI disease A curved gram-negative microaerophilic bacillus which causes most cases of gastritis; it is present in 10-50% of healthy young persons and up to 60% of those ≥ age 60 Epidemiology H pylori may be spread by houseflies–hand washing may ↓ transmission, by intrafamilial contact, or domestic cats Note: 90% of Pts with intestinal-type gastric CA have been infected by H pylori, which may be a co-factor for gastric CA, acting either to stimulate production of cellular mutagens or induce ↑ proliferation after cell damage; it has been implicated in antibiotic-responsive duodenal ulcers, and linked to other gastric lesions, benign and malignant Diagnosis Gastric Bx with special–eg, Diff-Quik stain, serologic tests–90-95% accuracy, urea breath test Disease course H pylori infection → chronic superficial gastritis, peptic ulcer disease, lymphoproliferative disease, ± → gastric lymphoma, chronic atrophic gastritis, ± → gastric adenoCA Management Proton-pump inhibitors–eg, omeprazole, lansoprazole, esomeprazole; antibiotics–amoxicillin, clarithromycin, metronidazole; ranitidine; bismuth subcitrate. See Duodenal ulcer, Gastric lymphoma, Urea breath test. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 5/bedroom persons/bedroom) Income (%<US$30,000/y) 59 58 [greater than or equal to] 1 72 72 Heliobacter pylori infected (%) Emergency dept. Effect of genetic differences in omeprazole metabolism on cure rates for Heliobacter pylori infection and peptic ulcer. The Pyloragen test developed by Hycor determines the presence of the Heliobacter pylori (H. |
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