Hedgehog Gene

Any of a family of genes critical in the structural development of organisms from the stage of fertilized egg to early embryo; HG products act in a gradient fashion, controlling the organization of the body shape and structures—e.g., limbs and digits, brain and spinal cord. Hedgehog genes encode hedgehog proteins
References in periodicals archive ?
If it turns out one of these genes is medically important, and they have to tell a patient - you have a mutation in your Sonic Hedgehog gene - it's a little difficult.
4,5) The PTCH gene encodes a receptor for the protein product of the sonic hedgehog gene (SHH), a member of the hedgehog family of genes that are involved in developmental patterning during embryonic development.
a privately held biotechnology company and leader in the field of developmental biology, today announced the extension and expansion of their existing agreement to collaborate on the discovery and commercialization of three cell differentiation factors from the Hedgehog gene family.
The paper, titled "Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and Parathyroid Hormone-Related Protein," describes the characterization of the Indian hedgehog gene, one of three members of the hedgehog family of developmental inducing molecules, and its regulation of the rate of cartilage differentiation.
NASDAQ: CRIS), a therapeutic drug development company, today announced the publication of preclinical data in the journal Circulation, showing that topical Sonic Hedgehog gene therapy accelerated wound healing in an animal model of diabetes.
The article entitled, "Sonic hedgehog gene therapy in myocardial ischemia: tissue repair through transient reconstitution of embryonic signaling" will appear in the November issue of Nature Medicine.
The scientists believe that HPE may arise from a combination of a faulty sonic hedgehog gene, present from conception, and varying times of exposure to environmental factors that further compromise the protein's signaling.
Kengo Kusano, the first author of the paper entitled "Sonic Hedgehog Gene Therapy in Myocardial Ischemia: Transient Reconstitution of Embryonic Signaling Preserves Cardiac Function," will compete as a finalist for the Melvin L.