SERPIND1

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SERPIND1

A gene on chromosome 22q11.21 that encodes a member of the serine protease inhibitor (serpin) family that rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. SERPIND1 shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.

Molecular pathology
SERPIND1 mutations are associated with heparin cofactor-II deficiency.
References in periodicals archive ?
Although the HCI system was not as sensitive as HCII system, at specificities (i.
In the HCII simulator, these people drove a course that included various traffic lights, stop signs and pedestrians while the researchers monitored their heart rate, pupil size, blink rate, brain wave activity and other measures of attention and cognitive load.
We are very excited with this opportunity to work with Carnegie Mellon's HCII graduate class," said John Degory, CEO of Cyrusoft International.
The company's common shares trade on the NASDAQ Global Market under the ticker symbol HCII and were recently added to the Russell Microcap Index.
Evan Jones, Chairman and Chief Executive Officer, Digene Corporation, commented, "We are pleased we have been granted FDA clearance for our HCII GC- ID Test for the detection of gonorrhea, following our recent clearance granted for our HCII CT-ID Test for the detection of Chlamydia.
The Digene HCII CT Test is a signal amplified nucleic acid hybridization assay that uses Digene's Hybrid Capture II technology to identify the presence of infection.
Common shares trade on the NASDAQ Global Market under the ticker symbol HCII and warrants trade on the same market under the ticker symbol HCIIW.