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diffuse infiltration of the thyroid gland with lymphocytes, resulting in diffuse goiter, progressive destruction of the parenchyma and hypothyroidism.
[Hakaru Hashimoto, Japanese surgeon, 1881–1934]
An autoimmune illness in which there is inflammation, followed by destruction and fibrosis of the thyroid gland, and ultimately resulting in hypothyroidism. Autoantibodies against thyroglobulin and receptors for thyroid-stimulating hormone cause the progressive destruction. Hashimoto thyroiditis is the most common cause of hypothyroidism where there are inadequate levels of iodine. It affects people of all ages but is most common in older women and in those with a family history of autoimmune diseases. Thyroid hormone replacement is required.Synonym: chronic lymphocytic thyroiditis See: thyroid gland
Hashimoto,Hakaru, Japanese surgeon, 1881-1934.
Hashimoto disease - Synonym(s): Hashimoto thyroiditis
Hashimoto struma - Synonym(s): Hashimoto thyroiditis