Hashimoto thyroiditis

Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

Ha·shi·mo·to thy·roi·di·tis

diffuse infiltration of the thyroid gland with lymphocytes, resulting in diffuse goiter, progressive destruction of the parenchyma and hypothyroidism.

Hashimoto thyroiditis

[Hakaru Hashimoto, Japanese surgeon, 1881–1934]
An autoimmune illness in which there is inflammation, followed by destruction and fibrosis of the thyroid gland, and ultimately resulting in hypothyroidism. Autoantibodies against thyroglobulin and receptors for thyroid-stimulating hormone cause the progressive destruction. Hashimoto thyroiditis is the most common cause of hypothyroidism where there are inadequate levels of iodine. It affects people of all ages but is most common in older women and in those with a family history of autoimmune diseases. Thyroid hormone replacement is required.
Synonym: chronic lymphocytic thyroiditis See: thyroid gland


Hakaru, Japanese surgeon, 1881-1934.
Hashimoto disease - Synonym(s): Hashimoto thyroiditis
Hashimoto struma - Synonym(s): Hashimoto thyroiditis
Hashimoto thyroiditis - diffuse infiltration of the thyroid gland with lymphocytes. Synonym(s): autoimmune thyroiditis; Hashimoto disease; Hashimoto struma; lymphadenoid goiter; struma lymphomatosa
References in periodicals archive ?
Hashimoto thyroiditis is observed with a 2-4 fold increased frequency in girls.
The coexistence of PCG and Hashimoto thyroiditis has been described in previous reports (10, 11) but is exceptional in a man.
11) Unlike PCG of the thyroid, solitary plasmacytoma of the thyroid is often associated with Hashimoto thyroiditis and subclinical hypothyroidism with elevated thyroid-stimulating hormone.
Patients with Hashimoto thyroiditis have a significantly increased risk of developing lymphoma, so long-term follow-up is required.
of Cytology Diagnosis Histologic Diagnosis Cases Papillary carcinoma Follicular adenoma + 1 Hashimoto thyroiditis Follicular adenoma 1 Multinodular goiter 1 Subacute granulomatous 1 thyroiditis Benign cystic nodule 1 Atypical adenoma 1 Positive for Hurthle cell adenoma 1 malignancy, NOS(*) (*) NOS indicates not otherwise specified.
13) In our study, we found that patients with malignancy and Hashimoto thyroiditis were more likely to develop prolonged temporary hypocalcemia following surgery.
Mucosa-associated lymphoid tissue lymphomas have been reported in association with disorders of the immune system, such as Sjogren syndrome[21] and Hashimoto thyroiditis,[22] suggesting that dysregulation of T-cell function may be involved in the genesis of MALT lymphoma in these patients.
Sera from individual healthy blood donors (n = 65), double-stranded DNA antibody-positive patients with systemic lupus erythematosus (n = 10), rheumatoid factor-positive patients with rheumatoid arthritis (n = 10), and patients with Hashimoto thyroiditis (n = 15) showed inhibition of TSH binding of <10%.