Hashimoto's thyroiditis

(redirected from Hashimoto's syndrome)
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Related to Hashimoto's syndrome: chronic lymphocytic thyroiditis

thyroiditis

 [thi″roi-di´tis]
inflammation of the thyroid gland, usually characterized by such symptoms as sore throat, fever, and painful enlargement of the gland.
atrophic thyroiditis a type of autoimmune thyroiditis with atrophy of the follicles and without goiter.
autoimmune thyroiditis any of various types of thyroiditis characterized by autoantibodies against the thyroid gland, resulting in hypothyroidism. The two major types are Hashimoto's disease and atrophic thyroiditis; Riedel's thyroiditis is a less common type.
Hashimoto's thyroiditis Hashimoto's disease.
Riedel's thyroiditis a chronic type of autoimmune thyroiditis with a proliferating, fibrosing, inflammatory process involving usually one but sometimes both lobes of the gland, which becomes hard and enlarged and adherent to the trachea and other adjacent structures. Called also Riedel's struma.
subacute lymphocytic thyroiditis painless, self-limited hyperthyroidism without the nonthyroidal features of Graves' disease; there is lymphocytic infiltration of the thyroid gland.

Hashimoto's thyroiditis

Autoimmune thyroiditis, Hashimoto's autoimmune thyroiditis, Hashimoto's disaease, lymphadenoid goiter, struma lymphomatosa A form of thyroiditis most common in ♀ age 30-50, presents as a diffuse firm thyroid enlargement and/or with a familial Hx of goiter, hypothyroidism, Graves' disease or antithyroid antibodies; other diseases with autoimmune substrate associated with HT include chronic active hepatitis, DM, megaloblastic anemia, PBC, rheumatoid arthritis, Sjögren syndrome Clinical Goiter, often little else, but, if extreme, esophageal or tracheal compression Lab Antimicrosomal antibodies; while euthyroid state is maintained, ↑ RAIU, ↓ TSH, normal T3, normal T4; with nonresponse to TSH, ↓ RAIU, ↓ T4, ↑ T3 which reflects maximum stimulation Management Hormone replacement Prognosis Excellent Complications Rarely, lymphoma

Hashimoto's thyroiditis

A common form of thyroid gland swelling (GOITRE). This form of thyroid gland inflammation affects mostly middle-aged women and is an AUTOIMMUNE disorder, due to attack by antibodies mainly to the protein thyroglobulin produced by the gland. Other antibodies are also present. The resulting inflammation causes pain and sometimes difficulty in swallowing from gland enlargement. There is reduced output of thyroid hormone (thyroxine) and replacement therapy may be needed. A short course of steroids is also effective. (Hakaru Hashimoto, 1881–1934, Japanese surgeon).

Hashimoto's thyroiditis

The self destruction of the thyroid cells from an autoimmune disorder.
Mentioned in: Hypoparathyroidism

thyroiditis

inflammation of the thyroid gland.

autoimmune thyroiditis
see lymphocytic thyroiditis (below).
Hashimoto's thyroiditis
see also hashimoto's disease, lymphocytic thyroiditis (below).
immune-mediated thyroiditis
see lymphocytic thyroiditis (below).
lymphocytic thyroiditis
progressive cellular infiltration of the thyroid gland, predominantly by lymphocytes, and replacement by fibrous tissue, resulting in hypothyroidism, associated with the presence of autoantibodies against thyroglobulin, follicular cell microsomes, and a second colloid antigen. It occurs in dogs, particularly Beagles, obese (OS) chickens, buffalo rats and primates. The disease has some similarity to Hashimoto's disease of humans.