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Hashimoto's thyroiditis |
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thyroiditis /thy·roid·itis/ (-i´tis) inflammation of the thyroid gland. atrophic thyroiditis a type of autoimmune thyroiditis with atrophy of the follicles and without goiter. autoimmune thyroiditis any of various types characterized by autoantibodies against the thyroid, resulting in hypothyroidism; the two major types are Hashimoto's disease and atrophic thyroiditis; Riedel's thyroiditis is a less common type. Hashimoto's thyroiditis see under disease. Riedel's thyroiditis a chronic type of autoimmune thyroiditis with a proliferating, fibrosing, inflammatory process involving usually one but sometimes both lobes of the thyroid gland, as well as the trachea and other adjacent structures. Hashimoto's thyroiditis The self destruction of the thyroid cells from an autoimmune disorder. Mentioned in: Hypoparathyroidism thyroiditis inflammation of the thyroid gland. autoimmune thyroiditis see lymphocytic thyroiditis (below). Hashimoto's thyroiditis see also hashimoto's disease, lymphocytic thyroiditis (below). immune-mediated thyroiditis see lymphocytic thyroiditis (below). lymphocytic thyroiditis progressive cellular infiltration of the thyroid gland, predominantly by lymphocytes, and replacement by fibrous tissue, resulting in hypothyroidism, associated with the presence of autoantibodies against thyroglobulin, follicular cell microsomes, and a second colloid antigen. It occurs in dogs, particularly Beagles, obese (OS) chickens, buffalo rats and primates. The disease has some similarity to Hashimoto's disease of humans. Hashimoto's thyroiditis Autoimmune thyroiditis, Hashimoto's autoimmune thyroiditis, Hashimoto's disaease, lymphadenoid goiter, struma lymphomatosa A form of thyroiditis most common in ♀ age 30-50, presents as a diffuse firm
thyroid enlargement and/or with a familial Hx of goiter, hypothyroidism, Graves' disease or antithyroid antibodies; other diseases with autoimmune substrate associated with HT include chronic active hepatitis, DM, megaloblastic anemia, PBC,
rheumatoid arthritis, Sjögren syndrome Clinical Goiter, often little else, but, if extreme, esophageal or tracheal compression Lab Antimicrosomal antibodies; while euthyroid state is maintained, ↑ RAIU, ↓ TSH, normal T3,
normal T4; with nonresponse to TSH, ↓ RAIU, ↓ T4, ↑ T3 which reflects maximum stimulation Management Hormone replacement Prognosis Excellent Complications Rarely, lymphoma How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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