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leukapheresis
(redirected from Harvesting leukapheresis)

   Also found in: Wikipedia 0.02 sec.
leukapheresis /leu·ka·phe·re·sis/ (loo″kah-fĕ-re´sis) the selective separation and removal of leukocytes from withdrawn blood, the remainder of the blood then being retransfused into the donor.
leu·ka·phe·re·sis (lk-f-rss)
n.
The removal of a quantity of white blood cells from the blood of a donor with the remaining portions of the blood retransfused into the donor.

leukapheresis
[lo̅o̅′kəfərē′sis]
Etymology: Gk, leukos + aphairesis, removal
a process by which blood is withdrawn from a vein, white blood cells are selectively removed, and the remaining blood is reinfused in the donor. It is a treatment or supportive care measure in patients with leukocytosis R/T leukemia. The white blood cells may be used for treating patients with blood deficiencies or for research. Compare plasmapheresis, plateletpheresis. See also apheresis.

leukapheresis
the selective removal of leukocytes from withdrawn blood, which are then retransfused into the donor. See also pheresis.

leukapheresis
Therapeutics The removal of blood to collect specific blood cells; plasma is returned to the body. See Apheresis Transfusion medicine The separation of leukocytes from whole blood with/without platelets with continuous or intermittent return of the RBCs and platelet- and leukocyte-poor plasma to a donor. See Cytapheresis, Hemapheresis, Plateletpheresis
Leukapheresis types  
'Harvesting' leukapheresis WBCs are donated from healthy subjects to immunocompromised and leukopenic Pts, which may be effective in short-term therapy of acute infections; long-term, Pts become either immunized against the donor antigens or infected with pathogens; 1010 granulocytes are needed for adequate 'coverage' against infections; to maximize the harvest, the donor receives corticosteroids
Reduction leukapheresis WBCs that compromise normal circulation are removed to temporarily relieve Sx of hyperleukemia–> 100 x 109/L; in a typical procedure, ± 6 liters of whole blood are processed to remove 5-10 x 109 WBCs


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