Hardy-Weinberg equilibrium


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Har·dy-Wein·berg e·qui·lib·ri·um

(har'dē wīn'bĕrg),
that state in which the genetic structure of the population conforms to the prediction of the Hardy-Weinberg law; it is not a stable equilibrium, although for a large mating population it may be approximated.

Hardy,

Godfrey H., English mathematician, 1877-1947.
Hardy-Weinberg equilibrium - the state in which the genetic structure of the population conforms to the prediction of the Hardy-Weinberg law. Synonym(s): random mating equilibrium
Hardy-Weinberg law - if mating occurs at random with respect to any one autosomal locus in a population in which the gene frequencies are equal in the two sexes, and the factors tending to change gene frequencies are absent or negligible, then in one generation the probabilities of all possible genotypes will on average equal the same proportions as if the genes were assembled at random.

Weinberg,

Wilhelm, German physician, 1862-1937.
Hardy-Weinberg equilibrium - see under Hardy, Godfrey H
Hardy-Weinberg law - see under Hardy, Godfrey H
References in periodicals archive ?
Three loci displayed significant departure from Hardy-Weinberg equilibrium expectations, likely reflecting occurrence of null alleles.
Pearson's chi-square test was used to check for Hardy-Weinberg equilibrium of the SNP detected in the sample population.
Chi square [chi square] test was used to evaluate Hardy-Weinberg equilibrium (HWE).
1619 and all loci exhibited no significant evidence of null alleles, but deviated from Hardy-Weinberg equilibrium based on testing of 60 unsexed individuals.
For the microsatellite data, Bonferroni-corrected tests for Hardy-Weinberg equilibrium and linkage disequilibrium were conducted using GENEPOP 4.
66) heterozygotes indicated the population was in or near Hardy-Weinberg Equilibrium (Table 2).
Deviations from Hardy-Weinberg equilibrium (HWE) were evaluated by Fisher's exact tests using the Markov chain (1,000,000 steps and 100,000 dememorization steps).
The genetic differentiation was observed in all population derived from both observed (Ho) and expected heterozygosity deviation from Hardy-Weinberg equilibrium.
Although there is no substitute for a firm understanding of the basic underlying quantitative features of the Hardy-Weinberg equilibrium and the resulting effects of violations of its assumptions, it can be very difficult to examine the long-term dynamics of population genetic processes with only a pencil-and-paper approach.
This software analyzes deviations from Hardy-Weinberg equilibrium following the procedure developed by Guo and Thompson (1992), based on the exact Fisher test.
The KL-VS allele frequencies were in Hardy-Weinberg equilibrium in both patient (p = 0.