haplotype

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haplotype

 [hap´lo-tīp]
1. a set of alleles of a group of closely linked genes, such as the HLA complex, which are usually inherited as a unit, an individual inheriting a complete haplotype from each parent.
2. the genetic constitution of an individual at a set of linked genes.

hap·lo·type

(hap'lō-tīp),
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. In immunogenetics, that portion of the phenotype determined by a set of closely linked genes inherited from one parent (that is, genes located on one of the pair of chromosomes).
[haplo- + G. typos, impression, model]

haplotype

/hap·lo·type/ (-tīp) the group of alleles of linked genes, e.g., the HLA complex, contributed by either parent; the haploid genetic constitution contributed by either parent.

haplotype

(hăp′lə-tīp′)
n.
A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

hap·lo·type

(hap'lō-tīp)
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. immunogenetics That portion of the phenotype determined by a set of closely linked genes inherited from one parent (i.e., genes located on one of the pair of chromosomes). The human major histocompatability complex comprises 4 recognized loci (A, B, C, and D) for which there are more than 50 alleles. Similarly, the allotypic markers (antigens) of the immunoglobulin subclasses IgG1, IgG2, IgG3, and IgA2 occur in combinations and are inherited as units almost always unchanged in transmission; the alleles that control these various haploptypes are not linked to those controlling the antigens of the κ type L chains.
[haplo- + G. typos, impression, model]

haplotype

The entire set of allelic variants that may be found at any particular genetic location.

haplotype

see HLA SYSTEM.

Haplotype

A set of alleles (an alternative form of a gene that can occupy a particular place on a chromosome) of a group of closely linked genes which are usually inherited as a unit.

haplotype

the group of alleles of linked genes contributed by either parent; the haploid genetic constitution contributed by either parent.
References in periodicals archive ?
When estimated according to combined copy numbers of N6AMT1 and AS3MT haplotypes associated with low %MMA, associations were consistent with an additive effect of variants in the two genes, such that women with two copies of the two haplotypes had the lowest mean %MMA (6.
demonstrated the ability to construct a fetal genomic map by combining maternal plasma DNA-sequencing data, paternal genotype information, and maternal haplotype information.
Genomic DNA was extracted and the frequency of the EPCR gene A3 haplotype 1651 C-G was screened via PCR using the primers 5'-GCTGAAATTTTGTATTCTGTCC-3' and 5'-CCAGTATAATGGCTACATTTTACC-3', and annealing at 54 [degrees]C.
COLLECTION DATA, HAPLOTYPES AND NUMBER OF SAMPLES FOE INCISITERMES MINOR AND INCISITERMES SNYDERI.
Moreover, the results agree with our anticipation that in each collecting site there were fewer haplotypes and lower haplotype diversity of A.
Sample sizes and the number of haplotypes within each species are presented in Table 2.
Plotting geographical distribution on the arrangement of haplotypes indicated that the coyote populations in the Cleveland area do not freely intermix.
Subsequently, the GGGTTT, GGGGTT and AAGGCC haplotypes were taken as reference genotypes.
The researchers confirmed the association between AD and the SORL1 gene by genotyping the single-nucleotide polymorphisms that were contained in the haplotypes and then analyzing them at an independent facility in three series of cases and controls of European ancestry from different Mayo Clinic centers (totaling 1,405 late-onset AD cases and 2,124 controls).
Our results indicate that alleles of A33, DR7, and haplotypes containing DR7 are associated with HBV chronicity among Koreans.
They found 10 common polymorphisms and inferred 5 major haplotypes.