Hand Foot Syndrome

A ‘crisis’ in sickle cell anaemia caused by sludging of red cells in vessels and characterised by symmetric infarction of the small bones of the hand and foot, periosteal neo-osteogenesis, pain and swelling that may occur as early as the age of 18 months, often resolving spontaneously within 1–4 weeks
References in periodicals archive ?
This delivery system does not encompass pegylation and yields very little hand foot syndrome
Hand foot syndrome in sickle cell anaemia (two case reports).
Drug-related adverse events (all grades) were consistent with those observed in previous clinical trials and included: rash, diarrhea, hand foot syndrome, hair loss, itching, nausea, hypertension, and fatigue.