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Haff Disease

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Haff Disease
A condition defined as rhabdomyolysis within 24 hours of ingesting fish. It occurred in ‘epidemic’ waves—1924, 1925, 1940—affecting ±1000 people who lived near Königsberg Bay, Lithuania, and was recently reported in the US—all 6 cases had consumed buffalo fish—Ictiobus cyprinellus
Aetiology Ingestion of fish tainted with cellulose-derived toxic resins and/or arsine from paper-processing plants that discharged waste into Haff waters had been postulated; more recently, an unidentified toxins in eels and fish have been blamed


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Haff disease associated with eating Buffalo fish--United States, 1997.
Although Haff disease is traditionally an epidemic foodborne illness, these six cases occurred in two clusters and as one sporadic case.
 
 
 
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