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The activity of laughing; the manifestation of mirth or joy, or, less commonly, sarcasm or scorn
Alternative medicine See Laughter club, Laughter therapy, Laughter yoga
Neurology Spasmodic and largely involuntary expirations often accompanied by inarticulate vocalisations, generally evoked by mirth
Physiology Laughter increases blood flow to the brain and activates neural networks—e.g., nucleus accumbens (NAcc) and amygdala. Functional MRI data suggests that the increase in blood flow to NAcc evoked by extreme humour is similar to that triggered by monetary gain or use of some addictive drugs; a key symptom of depression is the lack of a sense of reward from previously rewarding activities—e.g., humour
Psychiatry Laughter is regarded as the most effective coping skill for anxiety-panic disorders and may temporarily alleviate the symptoms of anxiety and depression


A series of inarticulate sounds produced as an expression of emotion, usually happiness or mirth. The role of humor and laughter in promoting a positive attitude and health and in preventing the progress of some diseases has been documented esp. when it is combined with proven medical therapies.

compulsive laughter

Laughter without cause, occurring in certain psychoses, esp. schizophrenia.

pathological laughter

Uncontrolled laughter (occasionally accompanied by, or alternating with, uncontrolled crying), caused by pseudobulbar lesions of the brain. These lesions may result from lacunar strokes, multiple sclerosis, anoxic brain injury, and other forms of brain injury.
References in periodicals archive ?
Along with the riotously picaresque first-person narrative of Ceremony of Innocence (1992) by Doyle's fellow Dubliner Anthony James Cassidy, Paddy Clarke Ha Ha Ha evokes the innocence and ingenuities of a modern urban preadolescent, a voice largely unheard in serious fiction heretofore.
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Doyle, pictured, won the Man Booker prize in 1993 for Paddy Clarke Ha Ha Ha, with the view of the world through the eyes of a 10-year-old.
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