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HTLV-I |
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HTLV-I, abbreviation for human T-cell lymphotropic virus type I. HTLV-I Virology A retrovirus that immortalizes T cells; it is associated with 1. Adult T-cell lymphoma/leukemia in endemic regions of southern Japan–where up to 40% of leukemic Pts are HTLV-I-positive, and the Caribbean 2. Chronic
progressive myelopathy–tropical spastic paralysis, a condition endemic to the Caribbean, tropical Africa, and South America and 3. HTLV-I-associated neuropathy; HTLV-I, like HIV-1, is blood-borne Carrier prevalence–US, Europe up to
0.10%; 1% of HTLV-I-infected subjects develop clinical disease, which may reflect host susceptibility and variant viral strains How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Viruses detected in HTLV-I associated myelopathy and adult T-cell leukaemia are identical on DNA blotting. Others are human papillomavirus (HPV), a cause of cervical cancer; HTLV-I, which can cause a rare cancer or a paralytic illness; mycoplasma, which causes urethritis; mobiluncus, which causes vaginosis; and human herpes virus 8, which causes Kaposi's sarcoma and lymphoma. The team's technique rapidly and unambiguously discriminates between HTLV-I and HTLV-II, Chen says. |
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