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HMG-CoA reductase inhibitor

   Also found in: Wikipedia 0.06 sec.
HMG-CoA reductase inhibitor,
any of a group of drugs that competitively inhibit the enzyme catalyzing the rate-limiting step in cholesterol biosynthesis and are used to lower plasma lipoprotein levels in the treatment of hyperlipoproteinemia. Also called statin .


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LIPOVAS (simvastatin) is an HMG-CoA reductase inhibitor co-developed by Merck & Co.
WARNINGS Myopathy/Rhabdomyolysis In clinical trials, there was no excess of myopathy or rhabdomyolysis associated with ezetimibe compared with the relevant control arm (placebo or HMG-CoA reductase inhibitor alone).
WARNINGS Myopathy/Rhabdomyolysis In clinical trials, there was no excess of myopathy or rhabdomyolysis associated with ezetimibe compared with the relevant control arm (placebo or HMG-CoA reductase inhibitor alone).
 
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