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HMG-CoA reductase
(redirected from HMG CoA)

   Also found in: Dictionary/thesaurus, Wikipedia 0.02 sec.
HMG-CoA reductase,
a rate-controlling enzyme of cholesterol synthesis. Activity of the enzyme may be as much as 60 times higher than normal in patients with low-density lipoprotein receptor disorder.


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Org Prep Proc Int 23: 133-138 Duane WC, Hunningnake DB, Freeman ML, Pooler PA, Schlojner L, Gebhurd RL (1988) Simvastatin, a competitive inhibitor of HMG CoA reductase lowers cholesterol saturation index of gallbladder bile.
Reducing the levels of HMG CoA reductase may help in the management of high cholesterol.
 
 
 
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