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HIV-associated dementia

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HIV-associated dementia (HAD),
a usually rapidly progressive dementia that is the primary manifestation of encephalopathy caused by human immunodeficiency virus type I infection. It is marked by a variety of cognitive, motor, and behavioral abnormalities, including loss of retentive memory, inattentiveness, language disorders, apathy, incoordination, and ataxia. As the disease progresses, paraplegia, urinary and bowel incontinence, abulia, and mutism may occur. Survival after the onset of dementia is usually 3 to 6 months but is occasionally longer.


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In addition, it was believed that these infected and underperforming cells are also the cause of HIV-associated dementia, which commonly occurs in the later phases of HIV infection.
HIV encephalopathy is part of the acute HIV syndrome during seroconversion whereas AIDS dementia complex, also known as HIV-associated dementia complex, is characterised by cognitive, motor and behavioural features in advanced AIDS when the CD4 lymphocyte count falls below 200 cells/[mm.
Twelve patients with HIV who tested within the normal range on neuropsychological tests were compared with 10 normal, HIV-negative controls, 11 HIV-infected patients with mild neurocognitive disorder; and 10 patients with HIV-associated dementia.
 
 
 
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