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AIDS dementia complex
(redirected from HIV-associated dementia)

   Also found in: Wikipedia 0.06 sec.
AIDS dementia complex
n.
The neurological disease complex that is sometimes experienced by AIDS patients, caused by neuron injury and death and characterized by cognitive impairment.

AIDS dementia complex
A type of brain dysfunction caused by HIV infection that causes difficulty thinking, confusion, and loss of muscular coordination.
Mentioned in: AIDS

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While decreases are observed in deaths from CMV, wasting, and HIV-associated dementia, increases are reported in deaths from sepsis, and diseases of the liver, kidney, and heart.
HIV-associated dementia may be due to the production of substances such as HIV proteins, cellular metabolites, and cytokines that may be toxic to neurons, oligodendrocytes or myelin.
Included is a table listing the major issues in the pathogenesis of HIV-associated dementia, which provides the next generation of questions for investigation.
 
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