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HIV-2

   Also found in: Acronyms 0.02 sec.
HIV-2,
n the abbreviation
for human immunodeficiency virus type 2, which is related to HIV-1 but carries different antigenic components with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian lentivirus simian immunodeficiency virus (SIV) and infects only T4-lymphocytes expressing the CD4 phenotypic marker.

HIV-2
LAV-2, HTLV-IV, SIV/AGM An immunodeficiency virus identified in West Africans with abnormal reactions to HIV-1 and simian immunodeficiency virus–SIV Clinical Some are similar to AIDS; others are relatively 'benign' Epidemiology HIV-2 is largely confined to West Africa and has an AIDS epidemiology pattern II–heterosexual transmission


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An enzyme-linked immunoassay (EIA) HIV screening test for HIV-1 and HIV-2 antibodies was required for all children <15 years of age who had received blood or blood products, had an HIV-positive mother, or in the judgment of the assessing medical practitioner, was noted to have any other identified HIV infection risk factor.
HIV-2, a less virulent variant of HIV which causes AIDS in people, also causes an AIDS-like syndrome in baboons.
While the finding doesn't reveal the origin of HIV, many scientists suspect that HIV-1 came from chimpanzees and HIV-2 from monkeys called sooty mangabeys.
 
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