HIV-2


Also found in: Acronyms.

HIV-2

Abbreviation for human immunodeficiency virus-2. See: human immunodeficiency virus.

HIV-2

LAV-2, HTLV-IV, SIV/AGM An immunodeficiency virus identified in West Africans with abnormal reactions to HIV-1 and simian immunodeficiency virus–SIV Clinical Some are similar to AIDS; others are relatively 'benign' Epidemiology HIV-2 is largely confined to West Africa and has an AIDS epidemiology pattern II–heterosexual transmission

HIV-2

Abbreviation for human immunodeficiency virus type 2.

HIV-2,

n the abbreviation
for human immunodeficiency virus type 2, which is related to HIV-1 but carries different antigenic components with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian lentivirus simian immunodeficiency virus (SIV) and infects only T4-lymphocytes expressing the CD4 phenotypic marker.
References in periodicals archive ?
During 1988-June 2010, health departments of the 50 states and the District of Columbia reported to CDC a total of 242 HIV-2 cases, based on a variety of criteria with no formal HIV-2 infection case definition.
Nonhuman primates infected with SIV from the currently recognized lineages can harbor antibodies that serologically cross-react with some HIV-1 or HIV-2 antigens (3).
Persons infected with HIV-2 typically have a slower development of immunodeficiency, and are less infectious in the early stages of infection.
Grossman, Sousa, and their colleagues recently showed that if people infected with HIV-1 and HIV-2 experience similar amounts of immune activation, their blood concentrations of CD4 T cells are reduced by about the same amount, though the HIV-2 carriers have much lower viral loads.
HIV-2 infections are predominantly found in Africa.
Among the 187 women without HIV-1 who started with an HIV-2 infection or contracted the virus during the study, only 7 showed subsequent signs of HIV-1, according to antibody and DNA tests of blood samples taken regularly from the women.
In January 1992, the team gave four additional baboons the same strain of HIV-2.
Now, a study of 574 prostitutes in Dakar, Senegal's capital, quantifies more precisely the characteristics of HIV-2.
Emphasizing that it is too early to assess the threat of HIV-2 in the United States, federal officials say there currently are no plans to specifically test the nation's blood supply for the virus.
He reports that his group has just completed mapping the entire genome, or genetic material, of an HIV-2 virus, and that they found the HIV-1 and the HIV-2 viruses to be structurally and functionally different.
At present, two major types of HIV have been identified, defined as HIV-1 and HIV-2.