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HIV-2 |
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HIV-2, n the abbreviation for human immunodeficiency virus type 2, which is related to HIV-1 but carries different antigenic components with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian lentivirus simian immunodeficiency virus (SIV) and infects only T4-lymphocytes expressing the CD4 phenotypic marker. |
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An enzyme-linked immunoassay (EIA) HIV screening test for HIV-1 and HIV-2 antibodies was required for all children <15 years of age who had received blood or blood products, had an HIV-positive mother, or in the judgment of the assessing medical practitioner, was noted to have any other identified HIV infection risk factor. HIV-2, a less virulent variant of HIV which causes AIDS in people, also causes an AIDS-like syndrome in baboons. While the finding doesn't reveal the origin of HIV, many scientists suspect that HIV-1 came from chimpanzees and HIV-2 from monkeys called sooty mangabeys. |
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HIV-2
