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HIV RNA

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HIV RNA
AIDS RNA of HIV origin, a serum marker of a Pt's 'HIV-ness,' now the standard by which Pt response to antiretovirals is evaluated; HIV RNA levels correlate with CD4+ count, response to antiviral therapy, clinical stage and disease progression. See AIDS, CD4:CD8 ratio, HIV, HIV tests, Reverse transcriptase, Western blot.


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In a stratified analysis, the proportion of patients with HIV RNA levels of fewer than 50 copies / mL was significantly greater with efavirenz than with lopinavir/ritonavir in the group that had 50 or fewer CD4 cells/m[m.
This is supported by the observation that increased plasma HIV RNA is associated with the enhanced risk of transmission amongst serodiscordant couples.
The authors found no clinically important differences in HIV disease progression according to mode of delivery as assessed by changes in CD4 count and HIV RNA during 18 months following delivery, and by progression to AIDS or death during a mean post-partum period of 2.
 
 
 
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