HELLP syndrome


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HELLP syn·drome

type of severe preeclampsia involving hemolysis, elevated liver function, and low platelets.

HELLP syndrome

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abbreviation for a form of severe preeclampsia, a hypertensive complication of late pregnancy. The letters stand for hemolysis, elevated liver function, and low platelet level.
A condition linked to eclampsia or severe pre-eclampsia, which is characterised by the acronym HELLP:
Hemolysis
Elevated Liver function tests
Low Platelets
Eclampsia may transiently worsen after delivery; other symptoms include blood pressure 160 systolic and/or 110 diastolic, urinary volume 400 mL/24 hours, nonspecific cerebral abnormalities, pulmonary edema, cyanosis
Lab Proteinuria 5 g/24 hours, schistocytes (RBCs sheared and fragmented by intravascular fibrin deposition), increased LFTs (ALA, AST, ALT, BR) increased PT; aPTT, normal fibrinogen levels

HELLP syndrome

Obstetrics A condition linked to eclampsia or severe pre-eclampsia, characterized by the acronym: Hemolysis, Elevated Liver function tests, Low Platelets, which may transiently worsen after delivery; other Sx include BP ≥ 160 systolic and/or 110 diastolic, urinary volume ≤ 400 mL/24 hrs, nonspecific cerebral abnormalities, pulmonary edema, cyanosis Lab Proteinuria ≥ 5 g/24 hrs, schistocytes–RBCs sheared and fragmented by intravascular fibrin deposition, ↑ LFTs–ALA, AST, ALT, BR, ↑ PT; aPTT, normal fibrinogen levels. See MTP complex.

HELLP syndrome

Acronym for haemolysis, elevated liver enzymes, low platelet syndrome.
References in periodicals archive ?
Patients lacking full criteria for complete HELLP syndrome, but having some of the diagnostic criteria for HELLP were considered to be suffering from partial HELLP and was confirmed by presence of at least any of the two laboratory criteria for full HELLP syndrome.
92 [micro]mol was found in pregnant women with HELLP syndrome, which is one of the most severe complications of PIH, whereas women with hemorrhages come next with 42.
In this study we present the concurrent fundus findings of one case of severe preeclampsia and one case of HELLP syndrome.
Liver infarcts with early HELLP syndrome and probable catastrophic antiphospholipid syndrome.
Vascular endothelial growth factor (VEGF) polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analyses.
HELLP syndrome can also leave other more serious effects on the baby, depending on the baby's age of development.
Of the patients who have severe preeclampsia, 4% to 12% will manifest criteria for HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet counts).
Key words: Pregnancy, fulminant hepatic failure, HELLP syndrome.
Barton and Sibai [8] found radiologic evidence of liver haemorrhage or infarction in 16 of 33 patients with HELLP syndrome who complained of right upper quadrant pain with neck or shoulder pain.
9,10 DIC occurs in pre-eclampsia 7%, HELLP syndrome (haemolysis, elevated liver enzymes, low platelets, pre-eclampsia) 30% and in acute fatty liver of pregnancy 90% of the time.
It turned out one midwife had been involved in a case where a woman had developed a rare condition called HELLP syndrome, which is like an extension of pre-eclampsia, and is life-threatening.
Lucy Owens had to give birth to her daughter Betrys Rose 15 weeks early via an emergency Caesarean section after she developed a life-threatening complication called HELLP Syndrome.