SERPIND1

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SERPIND1

A gene on chromosome 22q11.21 that encodes a member of the serine protease inhibitor (serpin) family that rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. SERPIND1 shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.

Molecular pathology
SERPIND1 mutations are associated with heparin cofactor-II deficiency.
References in periodicals archive ?
Under the agreement with Northstar, HC2 Network will acquire Northstar's broadcast television stations, which carry Azteca America programming.
HC2 -- a midsize, New York-based conglomerate -- held the call to go over fourth-quarter and 2016 earnings.
Currently, 4 HPV testing platforms are approved by the FDA for triage of a Papanicolaou test diagnosis of atypical squamous cells of undetermined significance (reflex testing) and as an adjunct to the Papanicolaou test (cotesting) in women 30 years and older: HC2 was approved for these purposes in 2003, Cervista in 2009, and Aptima and cobas in 2011 (cobas was further approved for primary HPV screening of women 25 years and older in 2014).
A 75 ng aliquot of the DNA was used for HC2 (Digene[R]) using both HPV high- and low-risk probe cocktails separately with the help of the Rapid Capture System in accordance with the manufacturer's protocol.
Sample BADCy Catalyst I Catalyst II HCI (a) HC2 (a) HC3 (a) (mol) (mol) (mol) (mol) (mol) (mol) BADCy 100 / / / / / BADCy/ 100 1 / / / / Catalyst I BADCy/ 2000 / 1 / / / Catalyst II BADCy/ 2000 / / 1 / / HC1 BADCy/ 2000 / / / 1 / HC2 BADCy/ 2000 / / / / 1 HC3 (a.
Hatchery Populations Genetic Variability Locus Indices HC1 HC2 Hka3 NA (size, bp) 14 (257-309) 10 (257-317) [R.
2) The HC2 test is reliable for detecting clinically relevant oncogenic HPV DNA.
Nearly 6,000 acres near Roosevelt National Park are in Little Missouri State Park, c/o Cross Ranch State Park, HC2, Box 152, Sanger, ND 58567; (701) 794-3731.
These two senior NCI scientists have co-authored, with the chief scientific officer of Digene Corporation, a total of 36 articles endorsing the only FDA-approved Digene HC2 HPV test in the U.
It's the Philip Falcone -led HC2 Holdings , and the company that's buying Azteca America just landed another low-power TV station.