FGF4

(redirected from HBGF4)

FGF4

A gene on chromosome 11q13.3 that encodes fibroblast growth factor 4 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF4 is required for normal limb and cardiac valve development during embryogenesis. It interacts with FGF receptors FGFR1, -2, -3 and -4.