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HA-1A

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HA-1A,
a genetically engineered antibody used in the treatment of gram-negative bacteremia and septic shock. The antibody binds to bacterial lipopolysaccharide. It is relatively free of side effects.


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The FDA rejected the results of two clinical trials of HA-1A sponsored by Centocor on grounds that the company took an early look at the preliminary results and changed the ground rules of the trials in midstream in a way that could have made the drug appear more effective.
In its first large-scale human tests, HA-1A seems to have worked exactly as it should.
 
 
 
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