H2-receptor antagonist drug

H2-receptor antagonist drug e.g. cimetidine (Tagamet) and ranitidine (Zantac); used to heal gastric and duodenal ulcers and control symptoms of oesophageal reflux (heartburn); contraindicated in the use of local anaesthetics (they act as competitive inhibitors of hepatic enzymes that break down local anaesthetic compounds)
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SB is the maker of Tagamet(R) (cimetidine), which for years has been the least expensive of the H2-receptor antagonist drugs for treating duodenal ulcers.